Atomic-level characterization and cilostazol affinity of poly(lactic acid) nanoparticles conjugated with differentially charged hydrophilic molecules

• María Francisca Matus,
• Martín Ludueña,
• Cristian Vilos,
• Iván Palomo and
• Marcelo M. Mariscal

Beilstein J. Nanotechnol. 2018, 9, 1328–1338, doi:10.3762/bjnano.9.126

• green-styled lines. Distances between NH2 groups from a cationic nanoparticle and the center of mass of the PLA core are represented in ten different blue-styled lines. Interaction energy (kcal/mol) between the PLA core and DSPE–PEG lipid portion. Ten lowest computed binding energy values for cilostazol

Cationic PEGylated polycaprolactone nanoparticles carrying post-operation docetaxel for glioma treatment

• Cem Varan and
• Erem Bilensoy

Beilstein J. Nanotechnol. 2017, 8, 1446–1456, doi:10.3762/bjnano.8.144

• suggested to result in a more effective brain tumor treatment when compared to chemotherapeutics administered as an intravenous bolus infusion. Keywords: bioadhesive film; cationic nanoparticle; core–shell nanoparticle; docetaxel; glioma; Introduction A brain tumor is known as an abnormal growth of

• administration for therapeutic nanoparticles help reduce systemic side effects, bypass BBB and improve efficacy of the drug by forming a constant drug reservoir directly at target site [43][44][45][46][47][48][49]. The goal of this study was to evaluate and characterize implantable cationic nanoparticle-loaded